CD274 and cancer: The functional consequences of lactylation critically reprogram cancer cells by: (i) activating transcriptional programs for oncogenes, EMT/metastasis factors, immune checkpoints (e.g., PD-L1), and drug resistance genes; (ii) enhancing DNA damage repair capacity; (iii) promoting pro-survival autophagy; and (iv) facilitating immunosuppression and angiogenesis.