Among the diseases mentioned in this paper, the diseases caused by LPS activating NF-κB are periodontal disease (Ding et al., 2013), esophageal cancer (Meng et al., 2019), colorectal cancer (Wang et al., 2021), Alzheimer’s disease (Qiu et al., 2021), cardiovascular disease (Lei et al., 2011) and MAFLD (Ding et al., 2019). Here, NFKB1 is linked to periodontal disorder.