CD40LG and antiphospholipid syndrome: Antiphospholipid autoantibodies (aPL)—including lupus anticoagulant (LA), IgG and/or IgM anti-cardiolipin autoantibodies (aCL), and IgG and/or IgM anti-β2 glycoprotein I antibodies (aβ2GPI)—are central to the diagnosis of antiphospholipid syndrome (APS), an autoimmune thrombotic disorder (3).