RAB5B and cancer: Conversely, the expression of RAB5B was significantly down-regulated (decreased) in BLCA, CESC, COAD, ESCA, READ, TGCT, UCEC and UCS when compared to their respective normal tissue counterparts (Figure 2C), that may be attributed to specific tumor microenvironment factors, genetic mutations, or the presence of different regulatory mechanisms affecting RAB5B expression in these particular cancers.