RAB5B and cancer: Subsequently, the difference of RAB5BmRNA between cancer tissues and normal tissues was analyzed by TIMER2.0 with tumor tissues marked in red and normal tissues in blue RAB5B mRNA was significantly increased in three kinds of cancers: CHOL, LIHC, and PCPG and significantly decreased in COAD, KICH, KIRC and READ as shown in Figure 2D.