IL1B and intervertebral disk degenerative disorder: Several noxious stimuli including H2O2, lipopolysaccharide, IL‐1β, tumor necrosis factor (TNF)‐ɑ, acidic pH, and high glucose, have been used to mimic IDD in vitro and in vivo, wherein MSCs‐derived EVs have shown proliferative and anti‐apoptotic effects.