IL6 and sarcopenia: Franceschi et al. (2000). In 2000, the first named this response the “inflammatory response-aging” phenomenon, and 2 recent studies have shown that serum inflammatory response factors (e.g., IL-10, IL-15, IL-6, etc.)correlate with sarcopenia, and that higher levels of systemic markers of inflammation seem to correlate with lower muscle strength and muscle mass (Pan et al., 2021; Tuttle et al., 2020).