Previous studies have consistently demonstrated that RPL36AL (Ji et al., 2022), NDUFA1 (Li et al., 2018), NDUFS5 (Zhuang et al., 2023; Yan et al., 2024), RPS25 (Suzuki et al., 2022), and COX7C (Wang et al., 2021) are associated with mitochondrial function and ribosomal structure in AD. This evidence concerns the gene NDUFS5 and Alzheimer disease.