Particle analysis (Figure 5M) revealed that the TMEM119-immunofluorescent area was increased by 213.26% in MMD-LB (20.08 ± 3.90/mm2), 229.48% in PD (21.12 ± 4.76/mm2), and 211.54% in PSP (19.97 ± 3.94/mm2) relative to the controls (6.41 ± 2.23/mm2). This evidence concerns the gene TMEM119 and supranuclear palsy, progressive, 1.