The densities of CD4+ cells in nigra parenchyma were significantly increased by 970.82% in the MMD-LB (559.08 ± 424.31/mm3), 623.09% in PD (377.53 ± 222.80/mm3), and 666.55% in PSP (400.22 ± 153.98/mm3) groups relative to the control (52.21 ± 33.68/mm3) group (p > 0.01 across groups; Supplementary Figure 2F). The gene discussed is CD4; the disease is Parkinson disease.