Relative to age-matched controls, the fluorescent intensity of CX3CL1 in the neurons with absent α-syn-positive or tau-ir aggregates was reduced to 9.86% in MMD-LB, 0.12% in PD, and 15.19% in PSP groups (p > 0.05). This evidence concerns the gene CX3CL1 and supranuclear palsy, progressive, 1.