Molecular Mechanism Analysis: Utilize spatial transcriptomics techniques (such as 10x Visium) to locate the expression pattern of CXCL14 in specific areas of IPF lung tissue (such as fibroblastic foci), combined with CRISPR interference technology to verify its spatial co-localization relationship with TGF-β1 (38, 39). The gene discussed is CXCL14; the disease is idiopathic pulmonary fibrosis.