Compared with participants with AIP below the median and hs-CRP levels less than 1 mg/L, those with concurrently elevated AIP and hs-CRP levels were more likely to live in rural, had a higher level of education, and demonstrated a lower prevalence of alcohol consumption and solid fuel use, but significantly higher rates of hypertension, diabetes, dyslipidemia and obesity. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.