However, when DCs were stimulated to cross-present the GL261-neoepitope peptide, mImp3,43 followed by rIL-12 (bottom image) incubation, the mouse tumor-derived CD8POS T cells secreted 7-times higher levels of IFN-γ compared with Fc sham controls (top image) (Figure 3A). This evidence concerns the gene IFNG and neoplasm.