IL12RB2 and central nervous system cancer: We confirmed that the expression profiles of relevant IL-12R genes (Il12rb1, Il12rb2, and Stat4) are comparable between human gliomas (Figure 2A) and the murine GB cell lines (CT-2A, GL261, and 005) (Table S2; Figures 2E and S3H), supporting the utility of these mouse models for studying IL-12-mediated mechanisms in GB.