STING1 and neoplasm: As a result, TMA‐NPs considerably improved the therapeutic efficacy of radiotherapy, inhibiting both primary large tumors and distant tumor growth.[65a] Mechanistically, the elevated levels of c‐di‐AMP triggered robust STING signaling cascades, promoting DC maturation and T lymphocyte activation, ultimately enhancing local and systemic antitumor immune responses.[65a]