TNFRSF10B and familial pancreatic carcinoma: In particular, glioblastoma U87MG and pancreatic cancer MIA PaCa-2 expressed all three target receptors DR5, VEGFR2 and integrin αvβ3 (Fig. 3A), and were highly sensitive to SRH-DR5-B-iRGD in vitro (Fig. 3B).