In this regard, both in SM and WB breasts, we found markedly upregulated the pro-inflammatory interleukin 1 beta (IL1B) and its receptor IL1R2; by contrast, numerous genes coding for different IL receptors (IL1R1, IL1RAP, IL17RA, IL17RD, IL2RA, IL20RA, IL21R, IL22RA2, IL2RG, IL5RA, IL13RA1) were upregulated in SM breasts only, which highlights for myopathy-specific differences. The gene discussed is IL22RA2; the disease is myopathy.