Comparison of the healthy Czech population from the 1000 Czech Genomes Project [53] with a group of our 200 MPN patients showed that the minor allele frequency (MAF) of the JAK2-R1063H in the healthy population is lower than in the group of MPN patients (1.67% vs. 2.50%; not statistically significant). This evidence concerns the gene JAK2 and myeloproliferative neoplasm.