Several frequently occurring coding neomers were also found in other known cancer-associated genes, such as tumor protein p53 (TP53), B-Raf proto-oncogene serine/threonine kinase (BRAF), and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA). The gene discussed is TP53; the disease is cancer.