ELP3 and amyotrophic lateral sclerosis: In a microsatellite association study of 1483 individuals (781 ALS patients and 702 controls) from three different countries (U.S.A., Belgium, and the UK), allelic variants of Elp3 were associated with ALS (P = 1.96 × 10−9) and were shown to correspond to a 59% reduction in ELP3 protein levels in the motor cortex of ALS patients compared to controls22.