Further studies revealed that vimentin regulated MSC migration mainly through Rab7a.210 In addition, MSCs promote the phagocytic activity of macrophages through mitochondrial transfer.211 Morrison et al.212 found that when human BM-MSCs and monocyte-derived macrophages were cocultured followed by stimulation with LPS or bronchoalveolar lavage fluid from patients with ARDS, the expression of the anti-inflammatory macrophage marker CD206 increased, and the phagocytic ability improved. Here, VIM is linked to acute respiratory distress syndrome.