Intriguingly, the comparison of probabilities between genetic groups revealed group-specific patterns of similarity that recapitulated other recent work8 (Figure 5B): UBTF-TD and DEK::NUP214 leukemias were predicted to be more similar to HSCs than others, and CBFB::MYH11 leukemias more similar to GMPs. Here, NUP214 is linked to leukemia.