MUTYH and mutyh-associated polyposis: Alternatively, a subset of patients will develop multiple colorectal adenomas due to biallelic mutations in the gene MutY Homologue (MUTYH) located on chromosome 1, resulting in an autosomal recessive syndrome called MUTYH-Associated Polyposis (MAP), with a well-documented high lifetime risk of CRC in 43 %‒100 % of cases.6