In addition, data available in public datasets regarding IL-8 transcript levels in tumor tissue show a qualitatively similar trend toward association with poorer survival outcomes in resected ccRCC and nccRCC alike, again suggesting that the prognostic/predictive impact of IL-8 is independent from either the source of assessment or the histological subtype. This evidence concerns the gene CXCL8 and nonpapillary renal cell carcinoma.