Among these, both IK and BK channels (Catacuzzeno et al., 2014; Sciaccaluga et al., 2010; Soroceanu et al., 1999; Turner et al., 2014), two of the most abundantly expressed K+ channels in GBM cells, have been consistently linked to GBM cell migration and invasiveness. This evidence concerns the gene KCNMA1 and glioblastoma.