Additionally, both postbiotics upregulated anti-inflammatory mediators Tgf-β1 (2.14 ± 0.10-fold vs 1.37 ± 0.01 for CFS) and Il-10 levels (2.52 ± 0.30-fold vs 3.37 ± 1.25 for CFS). The gene discussed is TGFB1; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.