Among these dsRNA-positive cells, 34% (209/604) of the rH234-infected cells exhibited PABPC1 nuclear accumulation, which is roughly threefold higher than the 13% observed in rWT-infected cells (128/1,005, P < 0.0001), suggesting rH234A infection triggering a stronger RNase L activation (Fig. 6D). The gene discussed is PABPC1; the disease is infection.