IFNB1 and infection: At 36 and 48 HPI, rH234A-infected cells showed significantly elevated mRNA levels of IFN-β (7.9- and 5.5-fold), IFN-λ3 (6.1- and 7.2-fold), and ISG56 (7.4- and 4.1-fold), respectively, compared to rWT infection.