Azarashvili et al. suggested that mt‐Cx43 could play a neuroprotective role in different neuropathological conditions, since its downregulation is linked to mitochondrial dysfunction and to the increase of infarct volume after cerebral ischemia‐reperfusion (Azarashvili et al. 2011; Hou et al. 2016). This evidence concerns the gene GJA1 and Cerebral ischemia.