However, none of these exchanging mechanisms in GBM tumor microenvironment (TME) have been linked yet to Cx43, even though studies have revealed the presence of Cx43 at the TMs, suggesting a role of Cx43 GJs‐mediated communication in TMs stabilization (Osswald et al. 2015; Weil et al. 2017). This evidence concerns the gene GJA1 and neoplasm.