Based on the TIMER analysis, the expressions of CXCL10, ICAM1, IL18, ITGAL, SOCS3, and TLR3 in LGG patients were inversely correlated with tumor purity and positively correlated with various immune cell types, including B Cells, CD8+ T cells, CD4 + T cells, macrophages, neutrophils, and dendritic cells. The gene discussed is ITGAL; the disease is neoplasm.