CXCL10 (C-X-C motif chemokine ligand 10) operates as a potent proinflammatory mediator that orchestrates diverse biological activities encompassing chemotaxis, differentiation, and activation of peripheral immune cells, as well as the regulation of cell growth, apoptosis, and modulation of angiostatic effects, with recent studies highlighting its pivotal role in glioma immunology. The gene discussed is CXCL10; the disease is glioma.