Conversely, our QuPath analysis of IHC slides from the HPA showed increased staining of LAT1 and ASCT2 in the endothelium of both LGG (Figures 2B, 2E) and HGG (Figures 2C, 2F), with staining intensity correlating with glioma grade. The gene discussed is SLC1A5; the disease is central nervous system cancer.