Similar to previous tudies, comparison of the number of antibody positive patients and antibody titers between the groups showed that the anti-TPO and anti-TG levels and the number of anti-TPO positive patients were significantly higher in the groups with deficiency or insufficiency of vitamin D, compared to the group with sufficient vitamin D (p<0.001, p=0.026, p=0.006, respectively). This evidence concerns the gene TPO and hyperinsulinemic hypoglycemia, familial, 4.