First, to our knowledge, this is the first study to examine the association between three different SNPs (Drosha rs493760 C>T, DGCR8 rs1640299 G>T, and Dicer rs1057035 T>C) in miRNA machinery genes and vitiligo risk in the Turkish population, finding a positive association between rs1057035 in the 3′-UTR of Dicer and increased vitiligo risk. This evidence concerns the gene DGCR8 and vitiligo.