TRIM21 and interstitial lung disease: Next, we corrected all pooled studies for associated factors on RP-ILD development in IIM patients using the trim-and-fill method, and our results showed that ferritin (>336 ng/mL) (n = 1), Gottron papules (n = 1), fever (n = 2), anti-MDA5 antibody (n = 1), anti-Ro-52 antibody (n = 2), anti-Jo-1 antibody (n = 2), anti-ARS antibody (n = 2), anti-Ku antibody (n = 1), CRP (>0.05 mg/L) (n = 3), ALT (>27.75 U/L) (n = 1), and age (n = 3) showed symmetrical funnel plots and unchanged statistics after supplementing with the corresponding literature.