Within our TCRγδ+ dataset, we also identified a novel cluster of effector-like CD8αα+ cells with high expression of Zeb2, Ccr5 and Gzmk. Zeb2 is linked to the terminal differentiation of effector CD8 T cells in infection models, whereas Ccr5 is associated with infection induced migration to the gut mucosa (84–86). This evidence concerns the gene CCR5 and infection.