Similarly, lentiviral-induced miR-210 overexpression in a rat model of osteoarthritis led to decreased IL-1β, IL-6 and TNF-α levels in synovial fluid, while enhancing chondrocyte survival and suppressing NF-κB signaling via p65 downregulation (57), further supporting a protective role of miR-210 in chondrocytes during inflammatory conditions. Here, TNF is linked to osteoarthritis.