CST3 and interstitial lung disease: The analysis showed that female sex, age, smoking, rheumatoid factor (RF), erythrocyte sedimentation rate (ESR), disease activity score 28 (DAS28), C-reactive protein (CRP), high UA, aspartate aminotransferase (AST), white blood cell count (WBC), neutrophil ratio (NEUT %), fibrinogen (FIB), albumin (ALB), globulin (GLB), cystatin C (Cys-C), glucocorticoids (GCs) use, immunosuppressive drug (ISD) use, diuretics use, and chronic lung disease (CLD) were all statistically significant risk factors for the incidence of ILD in RA patients (Table 2).