Sirt1 is involved in many biological processes such as drug resistance, energy metabolism, cell proliferation, tumour development, autophagy and apoptosis (Kitada et al., 2019; Liang et al., 2008; Michan and Sinclair, 2007; Ou et al., 2014; Packer, 2020). The gene discussed is SIRT1; the disease is neoplasm.