Complete response, CR;<br>Control group, CG;<br>Cyclophosphamide, doxorubicin, vincristine, and prednisone, CHOP;<br>Diffuse large B-cell lymphoma, DLBCL;<br>Interleukin-6, IL-6;<br>Non-Hodgkin’s lymphoma, NHL;<br>Natural killer, NK;<br>Partial response, PR;<br>Quality of Life Core Questionnaire-Core 30, QLQ-C30;<br>Research group, RG;<br>Stable disease, SD;<br>Thymidine kinase 1, TK1;<br>Vascular endothelial growth factor, VEGF. The gene discussed is IL6; the disease is diffuse large B-cell lymphoma.