In a multivariate logistic regression controlling for age, sex, history of hypertension, diabetes mellitus, ischemic heart disease, smoking and socioeconomic status, pre-morbid low ALT remained significantly associated with the occurrence of post COVID-19 CHF (OR—1.64, 95% CI −1.03 to 2.53, see Table 2, graphical abstract). This evidence concerns the gene GPT and COVID-19.