INS and diabetes mellitus: Moreover, exposure to airborne particulate matter, excess nutrients in water, and chronic stress from odor and noise from AFO/CAFOs can contribute to systemic inflammation and oxidative stress, which may be related to insulin resistance, metabolic processes, and the development of diabetes (Balti et al 2014, Dufour et al 2012, Lundberg et al 2017, Lind and Lind 2018).