Moreover, the total NKG7 mRNA expression in CD8+ T cells from patients with ITP was significantly increased compared with that of healthy controls (3.66, IQR: 1.52, 9.41 vs 1.00, IQR: 0.48, 2.75, patients vs controls, P < 0.001; Figure 1C) (ITP: n = 43, control: n = 23). This evidence concerns the gene CD8A and autoimmune thrombocytopenic purpura.