ALB and cancer: Regarding the second stage of formation and evolution of NPPC structures, kinetic models (Dell’Orco et al., 2012; Darabi Sahneh et al., 2013; Dogra et al., 2019) in cancer nanomedicine were used to interpret association and dissociation of plasma proteins like human serum albumin (HSA), HDL over NP, it highlights the possible role of NPs size in corona formation.