In Dravet syndrome specifically, PRS for intelligence, longevity, and epilepsy were significantly different to those seen in non‐SCN1A‐related epilepsy without other known monogenic causes;14 a polygenic background influences epilepsy phenotype in monogenic families.5, 6. Here, SCN1A is linked to encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.