Although the overall proportions of TAMs were unchanged in the scRNA-seq dataset (and validation immunofluorescence analysis on terminal tumour tissue; Fig. 5h and Extended Data Fig. 8o,p), reclustering of this population alone indicated that cells more closely resembling anti-inflammatory macrophages of the tumour core were enriched in the WT relative to tumours in Sarm1−/− mice44,45 (Extended Data Fig. 9a–d). Here, SARM1 is linked to neoplasm.