CSMD1 and schizophrenia: It is noteworthy that CSMD1 is also highly expressed in the central nervous system and strongly associated with the dysregulation of neuropsychological responses (Schizophrenia Psychiatric Genome-Wide Association Study Consortium 2011, Zhang et al. 2020), and is mediated by a promoter-associated lncRNA (Steen et al. 2013).