Expanding beyond STAT1, exploring Zc3h12c's regulation of parallel inflammatory pathways (e.g., NF‐κB) and its crosstalk with compensatory Zc3h12a networks will elucidate broader roles in fibrosis, cancer, and autoimmune disorders, positioning Zc3h12c as a multifaceted therapeutic node in inflammation biology. Here, STAT1 is linked to cancer.