CD9 and osteosarcoma: We observed that the membrane proteincomponents of the P-Fe3O4@Pal@HM contained CD9-Flagfrom osteosarcoma cells and PECAM-His from osteosarcoma-associatedHVECs, indicating the presence of HM derived from two distinct celltypes (Figure H).The hybridization success was also confirmed by fluorescent labeling.The experimental process is shown in Figure I. Furthermore, we observed that the hybridmembrane-coated NPs exhibited fluorescence of the two colors simultaneously(Figure J).