ABCG2 and cancer: SLC genes, which encode a family of over 400 membrane-bound transporters, have been widely targeted for drug development.(29)ATPases are enzymes that hydrolyze ATP into ADP, resulting in the release of phosphate ions,(30) while ATP synthases are mitochondrial enzymes located in the inner membrane responsible for synthesizing ATP through electron transfer gradients.(31)ABC transporters bind to ATP and play a role in various cellular processes, including cancer resistance, antigen processing, cell division, and immunity.(32)