VEGFA and atrophic macular degeneration: Dry AMD involves the degeneration of the neural retina, retinal pigment epithelium, and choroid in a process known as geographic atrophy, while wet AMD is marked by choroidal neovascularization (CNV), wherein, encouraged by vascular endothelial growth factor (VEGF), blood vessels from the choroidal vasculature undergo aberrant growth, penetrating and damaging the retina.3