Notably, the H. pylori strain NCTC11637 (CagA+/VacA+), but not SS1 or NCTC12908, resulted in a significant loss of the normal spherical structure (displaying a loss of structural integrity, with crumpling, folding, and curling into a ball) of NGOs after co-infection with EBV at 6 h post-microinjection (Fig. 2A and B, middle panels). The gene discussed is S100A8; the disease is coinfection.