In contrast, co-infection of each H. pylori strain, including CHP1, CHP2, CHP3, and CHP4, with EBV consistently induced changes in morphology and higher organoid cell density along with prolongation of infection time within a 24 h period when compared to the infection of EBV or H. pylori alone control groups (Fig. 3D). The gene discussed is TESC; the disease is coinfection.