We also observed decreased expression of the mesenchymal marker Vimentin in KPSC tissues (Figure 4B,E; Figure S4A, Supporting Information), indicating reduced metastasis capability of KPSC tumor cells, as epithelial‐to‐mesenchymal transition (EMT) is a critical step in metastasis.[32] Immunohistochemical staining was then used to analyze key histological markers of PDAC initiation and progression. The gene discussed is VIM; the disease is neoplasm.