Alpha‐smooth muscle actin (α‐SMA), used to identify cancer‐associated fibroblasts (CAFs) and pancreatic stellate cells (PSCs) in the stroma,[31] also showed a marked reduction in α‐SMA‐stained areas in KPSC tissues at 12 weeks (Figure 4B,D; Figure S4A, Supporting Information). This evidence concerns the gene ACTA1 and cancer.