Moreover, infarction promoted more strongly heart stiffness in Col15a1−/− mice than in the WT littermates when compared with the baseline values (23.2 kPa in WT AMI; P < 0.05 and 35.1 kPa in Col15a1−/− AMI; P < 0.0001) (Fig. 3J). This evidence concerns the gene COL15A1 and infarction.