ARG1 and depressive symptom measurement: These findings are consistent with those of a previous study, in which the authors proposed Nrf2 to be an intermediary molecule in the regulation of microglial function to induce an Arg‐1+ microglial phenotype that attenuates the neuroinflammatory response in depression.[53, 54] We accordingly speculate that ACT and FA have antidepressant and anti‐inflammatory effects associated with the regulation of the microglial phenotype, which is mediated via the Nrf2 signaling pathway.